Global Advanced Research Journal of Medicine and Medical Sciences (ISSN: 2315-5159)
October 2016, Vol. 5(10) pp. 264-268
Copyright © 2016 Global Advanced Research Journals

Full Length Research Paper 

Clinicopathological Pattern of Colorectal Cancer in Tabuk Region, Saudi Arabia

Ahmad Abdulazeem Abdullah¹, Mohammed Elnibras Mohammed¹, Omer Saad El-Zahrani², Mostafa Abdulrahman Mahmoud² and Ibrahim Abdullah Albalawi³*

¹Assistant Professors of Surgery, Department of Surgery, Faculty of Medicine, University of Tabuk, Saudi Arabia.
²Consultants of Medical Oncology at King Salman Armed Forces Hospital in North West Region, Tabuk.
³Associate Professor of Surgery, Department of Surgery, Faculty of Medicine, University of Tabuk, Saudi Arabia.

*Corresponding Author E-mail: drbalawi@yahoo.com; Phone: +966555668449

Accepted 21 October, 2016

Abstract

Colorectal cancer is a common cancer in Saudi Arabia. This study aims to investigate the clinical and the pathological features of the disease in Tabuk region. Records of all patients diagnosed with colorectal cancer at the three main referral hospitals in Tabuk region; King Fahd Hospital, King Khaled Hospital and King Salman military hospital between 2010 and 2014 were retrieved retrospectively. Seventy-two patients were included. Saudi patients were 67 (94.4%) while four patients were non-Saudi (5.6%). The mean age of the patients is 56.4 ± 15.1 years (21 to 89 years). The male to female ration is 1.7:1. Fifty patients (69.4%) presented as cold cases while the rest presented acutely. The most common presenting symptom was rectal bleeding (83.4%) followed by alteration of bowel habits (39.2%), abdominal pain (37.3%), weight loss (25.5), anemia (17.6%), abdominal mass (13.7%). Left-sided tumors accounted for 73.6% while right-sided tumors comprised 26.4%. The rectum was the most common affected site (36.1%) followed by the sigmoid colon (27.8%). Synchronous tumors were found in 5 patients (6.9%), and moderately differentiated (63.4%) adenocarcinoma (98.6%) were the major pathological features.91.1% of patients presented with advanced stage and 29.9% with metastatic disease. The clinicopathological features of CRC in Tabuk region is similar to other regions in Saudi Arabia. However, a higher percentage of patients tend to present with an advanced stage of the disease.

Keywords: Colorectal, Cancer, advanced stage, Tabuk, Saudi Arabia.